Page 28 - Essentia Vol 5 Issue 1

VOL V | ISSUE I | 5 AUGUST 2026 VOL V | ISSUE I | 5 AUGUST 2026
A BIANNUAL NEWSLETTER OF ASSAM CANCER CARE FOUNDATION A BIANNUAL NEWSLETTER OF ASSAM CANCER CARE FOUNDATION

densely packed malignant lymphoid cells, the nuclei and eosinophilic cytoplasm. Tumour cells
“sky”. The pattern reflects one of the fastest were diffusely positive for S100 and negative
proliferative rates seen in human malignancy, for epithelial, vascular, melanocytic and muscle
often approaching a Ki-67 index of nearly 100%, markers.
as macrophages clear abundant apoptotic
tumour cells. A slide review of an ileocaecal
growth from a nine-year-old boy showed diffuse
sheets of monomorphic atypical lymphoid cells
with scattered tingible-body macrophages.
Immunohistochemistry showed CD20 and CD10
positivity, with CD3, CD5, CD23, Cyclin D1 and TdT
all negative, and Ki-67 approaching 100%.

Low-Power view High-Power view:
Rhabdomyoblastic component

Low-power view: Classical ‘starry Low-power view: Classical
sky pattern’ ‘starry sky pattern’

S100 immunopositivity

Four Names, Four Stories

High-power view: Tingible-body macrophages
Ê Zuckerguss carcinoma
“sugar-iced” cervical adenocarcinoma
Case 3: Malignant triton tumour — a sea with superficial spread
god in surgical pathology
Malignant Triton tumour is a rare malignant peripheral Ê Burkitt lymphoma
nerve sheath tumour with rhabdomyoblastic “starry sky” pattern from macrophages
differentiation, named after Triton, the Greek sea amid rapidly dividing lymphoid cells
god, following early experimental observations Ê Malignant Triton tumour
linking nerve tissue to skeletal muscle formation. named after the Greek sea
These tumours are rare, highly aggressive, and god, showing nerve and muscle
often associated with neurofibromatosis type differentiation
1, presenting both a diagnostic challenge and
a striking example of tumour plasticity. A core Ê Pulmonary carcinoid
biopsy from a recurrent lower back swelling in a carcinoma-like in appearance, but a
57-year-old woman showed sheets of malignant true neuroendocrine tumour
epithelioid cells with enlarged, hyperchromatic

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